Tuesday, April 26, 2016

Researchers find potential new treatment target for deadly brain cancer



That’s the title of an abstract from the Ottawa Hospital Research Institute. The summary says “A key player in brain tumor formation has been found that may lead to new therapies for a deadly and incurable cancer. The study is the first to show that a protein called OSMR (Oncostatin M Receptor) is required for glioblastoma tumours to form. Glioblastoma is one of the most deadly cancers, resistant to radiation, chemotherapy and difficult to remove with surgery.”

I don’t have anything to add to the quotes from the lead author, which I’ve cut and pasted in the following:

"The fact that most patients with these brain tumours live only 16 months is just heartbreaking," said Dr. Arezu Jahani-Asl, the lead author who performed this research largely in Ottawa while she was a postdoctoral fellow co supervised by Dr. Michael Rudnicki at The Ottawa Hospital and the University of Ottawa and by Dr. Azad Bonni from Harvard Medical School and Washington University School of Medicine. "Right now there is no effective treatment, and that's what drives me to study this disease." Dr. Jahani-Asl is now an assistant professor in the Department of Oncology at McGill University and a principal investigator at the Jewish General Hospital, with a laboratory dedicated to how glioblastoma develops.


PS - Please excuse the the morbid black and white graphic, but I'm feeling awfully sad about this GBM and the near term options for victims which, at this moment, still seem to be slim and none. 

Copyright: <a href='http://www.123rf.com/profile_lightwise'>lightwise / 123RF Stock Photo</a>

2 comments:

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