Wednesday, October 31, 2012

Got Gliomas? Don’t Eat (for a bit)

According to an article posted on,   Valter D. Longo, director of the Longevity Institute at the University of Southern California, Davis, School of Gerontology, and his colleagues have published results of a new study which shows that a controlled fasting period lasting no more than 48 hours improved the effectiveness of chemotherapy and radiation therapy in mice with gliomas. (If you don’t know what gliomas is, be happy that you don’t.)

In previous research, Longo's team showed that short-term fasting made cancer cells vulnerable to the toxic effects of chemotherapy while protecting healthy cells. In the new study, the investigators tested the effect of starvation on glioma cells by depriving mice of food for 48 hours prior to radiotherapy or prior to chemotherapy with temozolomide, the standard therapeutic agent used after attempted surgical resection of glioma.

Compared with mice that underwent fasting alone or radiation alone, more than twice as many mice receiving both interventions survived to the end of the trial period.

1 comment:

Unknown said...

Hey there! Thank you for sharing your thoughts about glioma. I am glad to stop by your site and know more about glioma. Keep it up! This is a good read. I will be looking forward to visit your page again and for your other posts as well.
Mixed gliomas, such as oligoastrocytomas, contain cells from different types of glia.
Gliomas are difficult tumors to treat. Recently, several investigations into the nature of glioma tumors and glioma treatments have been undertaken.